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New paper published in Chemistry – A European Journal. We are glad to announce that the article was considered by the referees with the label of great significance, with only less than 20 % of the manuscripts being awarded with such distinction. In this work, we carry out the covalent functionalization of a NiFe-LDH using APTES molecules using a topochemical approach followed by the anion exchange reaction of a surfactant molecules prior to the grafting with the APTES molecules. The functionalized NiFe–APTES was fully characterized using X-ray diffraction, electron microscopy, thermogravimetric analysis coupled with mass spectrometry, 29Si solid state nuclear magnetic resonance or Mössbauer spectroscopy, among others. Moreover, the anion exchange capability for the NiFe–APTES was tested employing Cr(VI), resulting in an increase of 200 % of the anion retention. This report allows a new level in the tunability of LDHs opening the door to the synthesis of new hybrid materials and architectures. You can find the article here